I have just returned from the EBMT 2017 conference. I have met with most prominent world scientist in field of HSCT – and I am truly amazed by the results that were presented. Here are the most important observations:
- CIDP in Chicago – dr Burt presented amazing results of CIDP HSCT trial from Chicago. The publication is pending… but „lame will walk” seems to be the case here (and those youtube videos do not lie). JUST TO GIVE YOU ONE SIMPLE NUMBER: pre HSCT 30% CIDP patients could walk without aid (and 25% were on wheel chair) – 5 years post HSCT 80% needed no assist in walking and NONE were on wheelchair – simply AMAZING. I just hope that neurologists will send their patients for HSCT as soon as they get to read that publication.
- MS – dr Atkins shared some insights from his Lancet paper from 2016 (http://thelancet.com/journals/laneur/article/PIIS1474-4422(08)70138-8/fulltext) – EDSS after HSCT did not progress after 2 years have passed from transplantation – in the timeframe of 13 years of post HSCT observation. In his study 40% of patients has sustainded EDSS improvement.
- SSc – the big news – this is the first autoimmune disease that reached level „I” of recommendations for HSCT – what does that mean? – the HSCT just becomes the standard treatment of progressive form of this disease – the guidelines should be published soon. The MS status in guidelines is also about to change…
- Breast cancer – the addition of HSCT into treatment of triple negative form of breast cancer improves greatly the survival of patients. This is not autoimmune disease but the results are also very intriguing.
I had a presentation on new clinical trial on central line infection prevention and use of different forms of G-CSF in mobilization.
Summarizing: I am very happy with the progress. Now we have to wait for HSCT to become a level “I” option in Multiple Sclerosis. CIDP and Systemic Slerosis patients finally will get option of curative treatment.