Transplantation in Autoimmune Diseases – Diabetes type 1

Hematopoietic stem cell transplantation as a treatment of early diabetes type 1.

Rationale to do the transplantation:

Diabetes is autoimmune process. Immunoablation (destruction of the malfunctioning immune system) and autotransplantation of hematopoietic stem cells may destroy ‘bad’ cells that destroy beta cells. If there is enough of beta cells in pancreas, the insulin production will be restored and patient will stop using insulin injections.

Does it work?

We were the first center in Europe to start this transplantation type. With over 20 transplantations performed in diabetes we see that most of the patients will stop using insulin. Our first patient will soon arrive at 4 year mark without insulin. Around 30 – 50% of patients will not use insulin over 5 years with excellent glycemic control. Most of the patients that return to insulin will have reduced insulin need (some might take one injection a day).

Who is elegible for treatment?

The treatment is still considered experimental and is offered to adults over 18 years old.

Most important inclusion criteria: Diagnosis of diabetes type 1 in the last 6 weeks.

If I want to know more about the treatment?

Please read the following

Article from our study group.

Article from prof Voltarelli and Burt

If I am interested – how can I get this treatment?

Please contact me for further information.

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